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Additionally, compound 25h could remarkably inhibit cancer growth in established HCC827 xenograft mouse model at 50 mg/kg in vivo.
These results show that the incorporation of In2O3 in ZnO nanostructure can remarkably inhibit recombination of photo-generated electron-hole pairs and thus improve the photocatalytic activity.
Furthermore, SP could remarkably inhibit the expressions of microphtalmia-associated transcription factor (MITF) and p-p38 MAPK and stimulated p-p70 S6K1.
For in vivo tests, the nanoprobes showed excellent tumor targeting ability, long blood circulation time, and could remarkably inhibit the growth of tumor.
Oral intake of the low Mw fraction could remarkably inhibit the growing of human non-small cell lung cancer PC-9 cells in nude mice.
The improvement of the electrochemical performance and thermal stability are attributed to the LAS amorphous coating films that can remarkably inhibit the change of the structure, activate the cathode and offer the fast Li-ion diffusion pathways.
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Pharmacological inhibition of xCT remarkably inhibited proliferation of multiple cancer cells in vitro and attenuated tumour growth in vivo [ 13, 17].
The POD activity was remarkably inhibited by large quantity of ZnO nanoparticles (50 mg/L).
The CE-ECM scaffold facilitated chondrogenesis, however the CL-ECM scaffolds remarkably inhibited chondrogenesis of MSCs.
Additionally, GSK3β siRNA remarkably inhibited Wnt5a-induced RhoA activation, stress fiber formation and cell migration.
Overexpression of let-7c-5p in BV2 cells remarkably inhibited the microglial activation.
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