Sentence examples for remarkably high affinity of from inspiring English sources

Isothermal titration calorimetry experiments demonstrated the remarkably high affinity of OPB-31121 for STAT3 with Kd (10 nM) 2 3 orders lower than other STAT3i.

Therefore, and in conclusion, one cannot exclude that a remarkably high affinity of PrP to Aβ could be ascribed to a sub-pool of amyloid species, which is not necessarily the (most) toxic one.

TPEN, an uncharged polydentate ligand with nitrogens as donor atoms, has remarkably high affinity for a broad spectrum of metal ions, including copper, iron and zinc [ 4].

All the synthesized target compounds showed remarkably high affinity and selectivity towards CDK1B, compared to flavopiridol, with Ki values in the low nanomolar range (Ki = 0.35 0.88 nM).

CB[ n] and CB[ n]-type receptors display remarkably high affinity toward their target guests in water as exemplified by the CB[7]· 30 complex with Kd = 1.4 aM.

In addition, protein adsorption capacity was remarkably improved due to the high affinity of the nano-porous TiO2 surface for proteins.

This is most probably due to the high affinity of some catechols toward Fe3+ ions and the remarkably high stability of the complexes formed.

Using surface plasmon resonance, the binding affinity of the polyamide to its target sequence was determined to have a remarkably high nanomolar affinity with an equilibrium constant of 1.6 × 10 9 M. In addition, the polyamide binding affinity to a mismatched DNA sequence decreased by over 70-fold, thus implying the polyamide is specific for its target sequence.

The affinity constants determined on both, the purified receptor and LNCaP cells, indicated significantly higher affinity of the dimer.

We discovered that CB[ n] homologues (CB[7] and CB[8]) display remarkably high binding affinity (Ka up to 10 M–1) and selectivity (ΔΔ G) toward their guests, which renders CB[ n]s prime components for the construction of stimuli responsive host guest systems.

The biological function of the remarkably high methionine content of 17% in Cnidoin is intriguing.