Remarkably, all differentially expressed genes were found to be down-regulated genes in aggressive melanoma cells versus primary human melanocytes suggesting that loss of specific gene signatures may be a key event in the development of advanced melanomas (Figure 2B).
Remarkably, genes differentially expressed between species pairs in the common environment were similar to what had been previously identified in the wild.
As aforementioned, RBPs were remarkably enriched in differentially expressed genes in COAD, LUAD and LUSC.
Remarkably, the key areas differentially activated after OA exposure in the HAB vs. LAB rat lines [13] could be confirmed in this corresponding mouse model, supporting the notion that the altered brain activation pattern in HAB animals may be a generalized feature, being indeed characteristic of enhanced trait anxiety.
On the other hand, the 36°C heat shock treatment produced a remarkably high number of differentially expressed genes with the majority of genes being downregulated.
Comparison of expression profiles between the two areas revealed a remarkably large number of differentially expressed transcripts in both tissues, respectively 1,127 in the digestive gland and 2,432 in the gills.
Remarkably, the set of differentially expressed genes identified by these authors did not include any of the highly upregulated genes identified in the present study, suggesting that there are differences in response according to different species, with bovine macrophages responding differently than human macrophages.
Remarkably, >30% of the differentially expressed genes exhibited a male or female expression bias.
In the stationary phase, the number of genes that were differentially expressed increased remarkably.
Remarkably, only 50 transcripts were differentially expressed at both concentrations (Additional file 1: Figure S1).
