Sentence examples for remarkably defective from inspiring English sources

Remarkably, defective SMN complex function in snRNP assembly causes a significant decrease in the levels of a subset of spliceosomal snRNPs and preferentially affects the accumulation of U11 snRNP of the minor splicing pathway in tissues from severe SMA mice.

Remarkably, defective SMN complex function in snRNP assembly causes a significant decrease in the levels of a subset of snRNPs and preferentially affects the accumulation of U11 snRNP a component of the minor spliceosome in tissues of severe SMA mice.

Remarkably, tumors defective for both ATM and p53 were more prone to drug induced cell killing and tumors with functional ATM but non-functional p53 could be sensitized by pharmacologic suppression of ATM signaling [ 50, 51].

Remarkably, loss of HDAC2 causes increased H4K16 acetylation and defective chromosome condensation and segregation during oogenesis providing evidence for a critical role of HDAC2 during meiosis (Ma and Schultz 2013).

Remarkably, analysis of TALEN and CRISPR/Cas9 specificity using integrase-defective lentiviral vector capture revealed only one off-target site for one of the gRNAs and three off-target sites for both of the TALENs, indicating a high level of specificity.

B. pertussis fbpA mutants were defective in using unchelated iron for growth and, remarkably, were also defective in using the native siderophore and xeno-siderophores for growth.

Remarkably, the Quantum Hall signature of our devices remains robust, even though defective sample edges result from the beam exposure.

Remarkably, three other late BCG strains, BCG-Danish, -Glaxo, and -Frappier also contain a defective phoR gene.

Remarkably, the intensity of interaction between Exo70 and Arp2/3 correlated with invasive potential of cells, and expression of mutant Exo70 defective in interacting with Arp2/3 prevented invadopodia formation and matrix degradation [ 216].

The Defective Detectives.

Indeed, remarkably, genetic deletion of Parp1 rescued normal cerebellar ADP-ribose levels and reduced the loss of cerebellar neurons and ataxia in Xrcc1-defective mice, identifying a molecular mechanism by which endogenous single-strand breaks trigger neuropathology.