Remarkably, the crucial role of this terminal hydroxyl function is further underscored when it is replaced by isobutyl, ethylamine or 2,3-epoxypropyl groups in derivatives of the diclofenac series, which generate M-channel blockers.
Remarkably, the crucial TCR contact residues p6G/p8R remain in nearly identical orientations as in the previous simulation (see below).
But they have stayed remarkably healthy, a crucial factor given their style of play, which is built on a disciplined, now-instinctive understanding of one another's responsibilities on the field.
Although he, of all people, should have had the brains and the presence of mind to grasp what was coming — and he did; he went for a solitary drive, "filled with sadness," on the day the war began — he hewed to the customs of cabinet government, conceding the initiative to Lord Grey, his foreign secretary, and was remarkably passive throughout the crucial July days.
Optimizing mold structure is a crucial measure of remarkably reducing mold power consumption and saving electric energy.
Remarkably, in the movie's crucial drama — Noah's intention to end the human race by killing the offspring of his son Shem (Douglas Booth) and his daughter-in-law Ila (Emma Watson) — Aronofsky grafts onto the tale of Noah one of the most harrowing and morally troubling Biblical stories, Abraham's readiness to sacrifice his son, Isaac.
Remarkably, genes that play a crucial role in lipoprotein synthesis (APOB), cholesterol metabolism (ABCG8, CYP2C9, CYP2C19, CYP4A11, APO and CYP7A1), oxidation of lipids and palmitic fatty acids (MTMR7), and induction of lipogenic gene transcription (LPIN1) were up-regulated in H group in contrast to L group.
Mr. Olszewski is part of a crucial — and, polls show, remarkably large — group in the race between Mr. Kirk and his Democratic opponent, Alexi Giannoulias: the undecided.
Remarkably, cyanogenic compounds have become so crucial for some species such as burnet moths (Zygaenidae) that they not only sequester, but also synthesize these compounds de novo by convergent evolution of the biosynthetic pathways (Jensen et al., 2011).
Among her influences, by far the most crucial one is her own remarkably multivalent mind.
Remarkably, in quiescent cells, the transcription of crucial cystogenic target genes is maintained even in the absence of HNF-1β.
