Remarkably, c-Yes activation in CRC correlates more closely with poor prognosis [7], [8] than does c-Src activation.
Invertebrate STIMs, human STIM-1 and STIM-2 share several highly conserved protein domains including the EF-hand Ca2+-binding domain, the SAM domain, and the coiled-coil/ERM domain, but diverge remarkably C-terminal to the coiled-coil/ERM domain [12].
Remarkably, c-Myc deletion completely abrogated the immediate wave of apoptosis following both ionizing irradiation and cisplatin treatment, recapitulating the phenotype of p53 deficiency in the intestine.
The physical interpretation of temperature dependence of C ij showed that (a) values of C 11 decreases more steeply with enhancing temperature, (b) C 12, and C 44, are less sensitive to temperature for SrX, (c) C 11 is remarkably larger than C 12, and C 44, and (d) values of all aggregate elastic constants C ij are influenced by temperature dependence indicating that anharmonicity is substantial.
Shao et al. (2008) showed that application of FeSO4 remarkably increased Cd concentrations in roots and shoots of rice (Table 3).
These cultivars show remarkably high Cd accumulation in shoots and grains even compared to other indica cultivars under the moderately Cd contaminated soil and the non-Cd-contamintation soil (Uraguchi et al. 2009b).
Remarkably, the C domain inserts into the globular domain, providing the central strands ß19 and ß20 of the ß-sandwich structure (Figure 1B).
Remarkably, hMsd1-C-PACT rescued microtubule defects in hMsd1-depleted cells as efficiently as full-length hMsd1 (Fig 3C and D).
Remarkably, The C-terminal region of M. MwoI revealed no similarities to other sequences, with one prominent exception, namely the predicted TRD of the mC MTase M. SfiI (GenBank entry 2761010) with the BLAST expectation (e) value of 10-3.
Remarkably, the c domain was present in all the members of the II and III phylogenetic groups and was reminiscent of the c domain found close to the C-terminus of the typical PDIs of mammals and to the N-terminus of homologs of ERp72 [ 5, 19].
Remarkably, cytochrome c-injected oocytes whose caspase activity was inhibited after 10, 20 or 30 minutes all exhibited apoptotic death, with the time to development of apoptotic morphology unchanged in the 20 and 30 minute groups and only slightly delayed in the 10 minute group.
