When one does so, something remarkable happens: the supplementary axioms become forcing fragile.
One patient dropped out despite remarkable improvement (see Supplementary Figure 46).
Although the genes that encode most proteins related to flagellar biosynthesis and its regulation are highly conserved in sequence (>90% identity) among the 34 strains, the fliC gene, which encodes flagellin, shows remarkable sequence diversity (65 85%) (supplementary fig. S3 C and D, Supplementary Material online).
One of the remarkable features of mitoribosomes (with the exception of plants, see supplementary table S1, Supplementary Material online) is the absence of 5S rRNA.
By staining for CD31 (an endothelial cell marker) and FosB in the NAT region, we saw a remarkable co-localization of these markers (Fig. 6c; Supplementary Fig. 29).
The effect of miR-205 on E-cadherin and fibronectin expression was similar (although less remarkable) in H441 cells compared with H2170 cells (Supplementary Figures 2C and D).
In influenza-free ferrets, MDk/W452(H5N8) transiently elevated body temperature without producing any remarkable signs of illness after intranasal inoculation (10 EID50/mL) (Supplementary Figure S6A).
BrdU displayed remarkable effect at the early stage of reprogramming (Supplementary information, Figure S1B) and showed maximum effect if its treatment was maintained from day 3 to day 7 (Supplementary information, Figure S1C).
In addition, the effect of supplementary feeding on mortality might be more remarkable in a clinical setting where optimal management of opportunistic infections takes place.
Overall, these correlations, which were largely unchanged when controlling for sequence length (supplementary table S6, Supplementary Material online), suggest remarkable concordance between the patterning of DNA methylation, when present, and histone modifications across evolutionary time (Nanty et al. 2011).
We validated our approach in two independent data sets of more than 600 AML samples21, 22, demonstrating remarkable stability with an overlap of 80% of all associated gene sets (Supplementary Fig. 3a, b, Supplementary Data 4).
