There are some remarkable limitations to this study, mostly concerning the non-homogeneous series of patients, the different grades of deformity, untreated and previously treated patients, and the relatively short follow-up.
Despite their promise, NGS technologies also suffer from remarkable limitations: high error rates, enrichment of rare variants, and a large proportion of missing values, as well as the fact that most current analytical methods are designed for population-based association studies.
These drawbacks of conventionally obtained rainfall data impose a remarkable limitation on the application of distributed hydrological model.
Although our preliminary results are promising, several limitations in this study are addressed: (i) as the sample size is still small, further validations in large cohorts and in different ethnic groups are recommended; (ii) a remarkable limitation to this and other studies in this field is the lack of standardized procedures.
Alongside the low initial numbers of settlers that he planned for each scheme, the president inadvertently built remarkable damage limitation into his administration's policy from the outset, given most blacks' unwillingness to leave.
He described his early impression of her poetry as "coziness tinged with melancholy", displaying "dazzling powers all the more remarkable for their limitation".
In "The Middle Passage" (1962), Naipaul provides a remarkable analysis of the limitations of the West Indian writer: **{:.break one} ** Living in a borrowed culture, the West Indian, more than most, needs writers to tell him who he is and where he stands.
Although these studies suffer from a number of methodological limitations, the remarkable finding across these studies is the uniformity of RA prevalence rates in developed populations – approximately 0.5% to 1% of the adult population [ 11- 18].
Despite these limitations, it is remarkable that we were able to capture all the major effects of KCNE1 on the activation gating of KCNQ1.
Despite these limitations, it is remarkable to note that this study provides important insights on perceived threats that drive multiple care-seeking practices among pregnant women within urban Accra.
Although a number of GA-derivatives, such as 17-AAG and 17-DMAG have been developed as Hsp90 inhibitors with remarkable preclinical success, the major limitations of these molecules are their hepatotoxic activity, which is likely to be caused by the benzoquinone moiety present in their structure.
