Sentence examples for remarkable binding from inspiring English sources

Consistent with results from the yeast two-hybrid assay findings, the precipitation results proved that the Dok6 PTB domain binds to the activated TrkC receptor strongly in vitro, while no remarkable binding was found between Dok6 and TrkA or TrkB with activation or no activation.

These libraries yielded inhibitors with remarkable binding properties (subnanomolar Ki, >1,000-fold selectivity) despite the small molecular mass (~1,200 Da).

However, TCRs show remarkable binding plasticity and cross-reactivity between allo-antigens and auto-antigens34,35 auto-antigens34,35oreacthus propenablingndependent of their primautoreactivetarget.

Their functions, which are typically associated with a wide range of intermolecular interactions where IDPs possess remarkable binding promiscuity, complement functional repertoire of ordered proteins.

Among the synthetic compounds, 6,7-dihydrothieno [3,2-c]pyridin-5(4H -yl amide 19 exhibits a remarkable binding affinity to the N-terminus of Hsp90 in a fluorescence polarization (FP) binding assay (IC50 = 50.3 nM).

It is a highly potent α2 adrenergic agonist with a remarkable binding specificity for the α2 adrenoceptor.

Starting with the bare protein of an MMP-13 X-ray crystal structure (PDB code: 2OW9),[ 8] we probed the selectivity-enabling, non-zinc-binding S1′-binding site of the protein in silico with uracil for preferred H-bonding interactions, and found a remarkable conserved binding motif of the uracil molecule within this allosteric binding site).

These pyrrolobenzodiazepine conjugates have exhibited remarkable DNA-binding affinity and improved solubility in water, a representative compound 7d showing promising in vitro cytotoxicity.

These fluoro substituted pyrrolo[2,1-c][1,4]benzodiazepines pyrrolo[2,1-c][1,4]benzodiazepinesability and most of thaveposhown premarkablenticancer activity, having GI50 values in micromolar to nanomolar concentration range.

Finally, in the fifth column, it would be remarkable if ligand binding to free dimer differs from ligand binding to free monomer, yet somehow, binding of the first ligand returns the unoccupied dimer subunit to a state indistinguishable from that of the free monomer (with respect to its ligand binding affinity).

It is remarkable that TR binding at any of the three promoter regions effectively generates repression (e.g., LacI binding of L1 in F1, F3 and F5).