Sentence examples for remains altered from inspiring English sources

For the majority of subjects, the expression of this set of 55 rapamycin-regulated genes is altered early in the disease process and remains altered in later stages.

Pine Point was an extensive open pit mine where failed attempts at remediation have resulted in a landscape that remains drastically altered 25 years after closure.

We additionally examined the connectome's topology after removing subcortical structures (d), with results suggesting that in the absence of subcortical regions, the topology remains minimally altered, likely thanks to alternative routing via cortico-cortical connections.

It remains unclear how altered functional activity can lead to the morphological disarray observed for FHC hearts.

The clinical value of using specific TET inhibitors to restore proper hydroxymethylation patterns in cancers where these are altered remains to be explored.

However, lacking a systematic study of the frequency and biological effects of non-synonymous variants, it remains unclear which altered functions are meaningful markers of clinical pathogenicity.

Although cutaneous primary afferent neurones are known to have lowered thermal thresholds in inflammation, whether their mechanical thresholds are altered remains controversial.

It is not clear whether the precursor peptide is cleaved from these sigma factors and whether sigma factor activity remains or is altered.

Very similar cleavage activity was observed in total protein extracts of frataxin-overexpressing and control cells, indicating that the ISC-independent enzyme OGG1 remains unaffected by altered ISC synthesis rates.

However, it remains uncertain if altering the solubilizing agent leads to differences in the conformational states of MPs in the gas phase and whether any general "rules" of which particular solubilizing agent is optimal for different MPs, or if each MP will behave differently, remain to be resolved.

More importantly, even if dosage were acting as a confounding factor in this way, the implication for clinical practice remains the same: altering the treatment of a patient who is otherwise stable is associated with a rise in the risk of relapse and hence should be avoided.