Sentence examples for remains a considerable challenge from inspiring English sources

However, comprehensive structural and chemical characterisation of such nanostructured coatings remains a considerable challenge.

Management of severe traumatic lower extremity injuries remains a considerable challenge.

Nevertheless, the comprehensive annotation of eukaryotic genomes remains a considerable challenge.

Appropriately informing decision-makers about longer-term, wicked policy issues remains a considerable challenge for the scientific community.

Although widely used clinically, the optimum balance between cell removal and the disruption of matrix architecture and surface ligand landscape remains a considerable challenge.

However, a universal index that is applicable to various plants remains a considerable challenge, primarily due to the limited range of field-measured datasets.

The grafting of Cr III) coordination complexes as capping units onto polyoxometalates (POMs), still remains a considerable synthetic challenge due to the difficulty in replacement of aqua-ligands in [Cr(H2O 6]3+ complexes.

Although vaccine development is an undisputed public health priority, it remains a considerable scientific challenge due to the four antigenically distinct serotypes and possible risk factors associated to vaccination and disease severity [26].

The effective treatment of focal neocortical epilepsies not satisfactorily responsive to systemic antiepileptic drug (AED) therapy remains a considerable clinical challenge.

Treatment of patients with acute mania remains a considerable medical challenge since onset of action of antimanic medication is delayed for several days.

It remains a considerable diagnostic challenge, especially in the absence of pulmonary infection, as the disease can mimic various gastrointestinal disorders, particularly the inflammatory bowel disease, colonic malignancy, or other gastrointestinal infections [ 7, 12].