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However, to date, research has been mainly focused on FDCA-polyesters synthesis, while synthetic routes to afford poly((ether)ester)s remained unexplored until the present study, despite their inherent value.
However, the biological properties and the mechanism of xanthan adjuvanticity are not clear and have remained unexplored until recently.
The molecular structure of membranes remained unexplored until the major breakthrough made by Gorter and Grendel in 1925.
It is also striking that ever since its discovery in the late 1970s the actual contribution of EpCAM to carcinogenesis remained unexplored until very recently.
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Not only did this make it easier to police the region — British patrols could go much farther upriver without having to cross borders — it also enabled British gold diggers [5] to travel farther inland as well (at least in theory: most of New Guinea's heavily forested and mountainous interior remained unexplored by Westerners until the early 20th century).
Furthermore, RelB modulation of cytokine and TNFα activation in microglial cells is an area that may have significant importance for understanding HAND pathology, yet until now has remained unexplored.
For example, the recent spate of publications implicating non-coding RNA in neurodevelopmental pathways (Kosik 2006; Cao et al. 2006; Berezikov et al. 2006) highlights areas of the genome that would until lately have remained unexplored by candidate gene studies searching for genetic influences on human cognition.
They remained unexplored.
Why exactly that would be the case, however, remained unexplored.
However, the associated biomechanics have remained unexplored.
The caves remained unexplored for so long because of the difficulty of probing their flooded interiors.
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