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As President from 1994 to 1999, he was revered less for his governance than as a figurehead, and even in retirement or, as he put it, when he withdrew further from public life, in his "retirement from retirement"—he remained the binding spirit of post-apartheid South Africa.
As President from 1994 to 1999, he was revered less for his governance than as a figurehead, and even in retirement — or, as he put it, when he withdrew further from public life, in his "retirement from retirement" — he remained the binding spirit of post-apartheid South Africa.
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ANT1 R79A mutant, which overlaps the binding site with haem or atractyloside, remained the haem-binding activity, but K22A and R279, the haem-specific binding residues, disrupted its binding completely.
As shown in Fig. 2F, while ANT1 R79A mutant remained the haem-binding activity, K22A and R279A could not bind to haem.
In our initial configuration from the docking, both Arg and Arg were initially within 5 Å from GABA (considering any atom of the residues), which remained in the binding pocket for all the simulations, although the carboxylate group was closer to Arg and remained too far from the side groups of Arg to form hydrogen-bond interactions.
The aggregates interacted through the noncovalent bonds and remained with the binding activity.
Molecular dynamics (MD) simulation show that EN and N1 remained in the binding pocket similar to the docked pose of EN-InhA and E1-InhA complexes and also suggested that InhA binds to its inhibitor in inhibitor-induced folding manner.
At each time point, "energy metabolism", "translation" and "transport and binding" remained the top three orthologous groups with the highest percentage of down-regulated genes.
The first half of the conserved motif of the predicted Zur-binding site was changed from GTAA to ACCG, leaving unchanged the remaining of the binding sequence.
Notably, two water molecules (W1 and W2 in Figure 1) were also found to remain in the binding pocket, contributing to a stable network of hydrogen bonds involving residues Thr, Gln and Thr of EGFR-TKD.
Where collective defence is concerned, we attach importance to NATO's remaining the indispensable link binding the United States to Europe's security interests, and we continue to attach great importance to the maintenance of good transatlantic relations.
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CEO of Professional Science Editing for Scientists @ prosciediting.com