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However, except for mouse models, their characterization and their origins have remained controversies in other models including humans.
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However, there still remain controversies in this field, such as the precise roles of bulk and surface oxygen vacancies (VO).
There still remain controversies on the principle of microwave desulfurization at present, thermal effects or non-thermal effects.
To resolve some of the remaining controversies, further carefully designed randomised controlled trials in GDM with long-term follow-up of both mothers and babies are necessary.
Locke argues that only by establishing political society with a legislature that makes known and settled laws and establishing a judiciary that resolves remaining controversies between people and having an executive power that enforces the laws can people's rights and freedoms be protected.
However, there remain controversies regarding downstream TAM signaling events, and different pathways may also be triggered in different cell types.
Two consensus meetings were held with national and international experts in the field, from academia, clinical backgrounds, industry and health policy groups to reach consensus on final assumptions and resolve any remaining controversies.
Yet, there remain controversies as to whether the FIE rates are fast enough to represent a significant management concern (Jørgensen et al. 2007 and replies; Kuparinen and Merilä 2007; Andersen and Brander 2009).
Although lymph node metastasis and advanced Pathological Tumour-Node-Metastasis stage are widely accepted prognostic indicators for colon cancer (O'Connell et al, 2004), methods for assessing lymph node involvement and heterogeneity within tumour classifications remain controversies (Johnson et al, 2006; Wang et al, 2008).
To address these, high-number, multi-institutional studies with limited heterogeneity in assessment and treatment protocols will better enable clarification of some of the remaining controversies in the treatment of CPM, and serve as a platform for incremental advances towards the optimal treatment of metastatic CRC.
One of the remaining controversies surrounds the role of the large-scale motion of the FeS head domain (17), which during the catalytic cycle moves between the states where the FeS cluster approaches the Qo site (Qo position) and the states where it approaches heme c1 (c1 position).
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