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One interpretation is that CNVs are relatively deleterious (compared with SNPs) and that natural selection often removes them from a population, following which little genetic variation in the form of CNVs may remain to characterize population differences.
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MDR is a major mechanism of treatment resistance in a variety of human tumors, and clinically applicable strategies to circumvent MDR remain to be characterized.
However, except for a few (pyoverdine, pyochelin, enterobactin), the vast majority of P. aeruginosa siderophore receptor genes still remain to be characterized.
In summary, human disorders caused or influenced by abnormal clock setting remain to be characterized.
However, the molecular details of the heterologous interaction remain to be characterized.
However, many leptospiral coding sequences (CDSs) still remain to be characterized [64].
The molecular mechanisms controlling HuR trafficking between different germ cell compartments remain to be characterized.
Otherwise, indirect factors that remain to be characterized might contribute to the embryonic development of an unconditional stimulus-response loop.
Additionally, there are a plethora of inflammatory genes and SNPs that remain to be characterized in association with trachoma.
Although it has been shown that dolphins possess active non-protein antioxidant molecules to cope with ROS generation [7], these molecules remain to be characterized.
Diabetic macrophages produce high levels of pro-inflammatory cytokines [8], [9].The causative factors underlying the chronic inflammatory state of diabetic wounds remain to be characterized.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com