Exact(17)
In an alternative model of genetic obesity, LXRα/β-deficient ob/ob mice remain obese and have increased adipose lipid storage, but display reduced hepatic lipid accumulation and improved insulin sensitivity compared to ob/ob mice [ 7].
This change is clinically important since boys and girls with severe obesity are very likely to (i) remain obese into adulthood [ 3] and (ii) suffer from adverse metabolic health consequences including an increased risk of type 2 diabetes, cardiovascular disease, hypertension, nonalcoholic fatty liver disease, and the metabolic syndrome [ 4, 5].
Although a recent Galllup-Healthways report shows the U.S. obesity rate has held steady, a whopping 26.2percentt of adults remain obese.
Children in this group were more likely than not to remain obese by age 35.
And 68percentt of respondents said it was riskier — not safer — to remain obese than to have weight loss surgery.
Like the Soviet military, the Pentagon, in other words, is planning to remain obese whatever else goes down.
Similar(43)
Similarly, although (diet-induced) obesity-prone rat pups cross-fostered to obesity resistant dams remained obese, they had improved insulin sensitivity as adults; in contrast, obesity resistant rat pups cross-fostered to genetically obese dams showed a diet-induced increase in adiposity, reduced insulin sensitivity and changes in hypothalamic neuropeptide expression [8].
Offspring from obesity-prone rats remained obese even when they were suckled by lean dams [3].
Duration of obesity from adolescence to young adulthood was based on obesity status at waves II, III, and IV and categorized as as follows: 1) never obese; 2) incident obesity (nonobese at baseline and became and remained obese at last examination); 3) fluctuating obesity (any shift in classification from obese to nonobese); and 4) persistent obesity (obese at all waves).
In a review of surveys from 1970-92, about half of obese school-age children remained obese in adulthood.
"It's the same for B.M.I. — for an obese child, the chance of remaining obese as an adult is very high".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com