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The phrase "remain largely unexplored" is grammatically correct and can be used in written English.
It is typically used to describe a situation or topic that has not been extensively studied or investigated. Example: Despite advances in technology, the deep sea remains largely unexplored.
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Stem cell regulation and hierarchical organization ofhuman skeletal progenitors remain largely unexplored.
The real effects of activism on other firms, stakeholders, institutions, and markets remain largely unexplored.
But changes in organizational structure and procedures of firms remain largely unexplored.
When black and white do interact, the conflicts remain largely unexplored.
However, its fracture behavior and associated microscopic mechanisms remain largely unexplored.
However, the functional contributions of LncRNAs to adipocyte or osteoblast differentiation remain largely unexplored.
However, the effects of DCS during the induction of endogenous synaptic plasticity remain largely unexplored.
However, the environmental factors that regulate contaminant body burdens in nearshore terrestrial consumers remain largely unexplored.
Yet the ethnic origin and genetic architecture of Tibeto-Burman speaking populations remain largely unexplored.
The effects of density dependence on the evolution of lifespan and mortality remain largely unexplored.
Post-transcriptional mechanisms, such as control of mRNA stability, remain largely unexplored.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com