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Indeed, Ser-to-Ala substitution mutants of STIM1 do not dissociate from EB1 under store depletion conditons, and Ser-to-Glu mutants remain dissociated from EB1 even under resting conditions.
Instead, we only see a slight reduction in kcat upon the introduction of oxygen to the reaction sample, this suggests a significant proportion of radical pairs remain dissociated until the substrate is exhausted.
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This implies that a small amount of residual structures remain in the dissociated water, but unfortunately they cannot be confirmed with Raman micro-spectroscopy.
His cohorts are just as dissociated, remaining inexplicably calm in the face of endless explosive disembowelment.
The negative zeta potential value is the evidence that the remaining number of dissociated functional groups is directed toward the bulk solution.
Inactive RNP and hTR-free TERT would remain bound as well as some active RNP not dissociated from product, and also any 293T TERT bound to DNA indirectly through an associated shelterin complex.
53 For reasons that remain unclear, insulin resistant subjects typically have selective or dissociated hepatic insulin resistance; that is, they have impaired insulin-mediated glucose homeostasis (mediated by the FoxO1 pathway) but enhanced insulin-mediated hepatic DNL (mediated by the SREBP-1c pathway).
One of the two dissociated trimers remained in the crystal edge for ∼0.9 s.
The DMN was one of the first resting networks to be extensively studied, and early findings on the DMN still hold [12], in that the main areas identified to be part of this network remain the same despite a multitude of studies, there is increasing evidence that the DMN may comprise multiple dissociated components [13].
Above 50 mM SDS, the θ208/θ222 was greater than 1 and remained unchanged, suggesting a stable conformation of dissociated proteins.
In the opposite of adherent cultured cells, all dissociated cells maintained in suspension remained in a round shape.
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