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Later stages of Th17 cell differentiation (clonal expansion, phenotype stabilization with IL-17 production) also rely on expression of IL-23, which is a potent inducer of IL-17 [13, 13].
To acidify intracellular organelles all eukaryotic cells rely on expression of multimeric vacuolar H+-ATPase proton pumps.
This led us to believe that B2KO protection might rely on expression and function of other molecules not measured here.
This study supports the idea that a PPI network integrated with expression data may further assist researchers in identifying potential disease markers or therapeutic targets, which might be overlooked when results rely on expression profiling analyses only.
These approaches will rely on expression of Cas9 and the sgRNAs from promoters of interest.
Unsupervised methods rely on expression data only but tend to achieve lower prediction accuracies than supervised methods [ 3, 9, 10].
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Everything I do, I try to do relying on expression and visual contact".
The concept relies on expression of gene products to generate specific antibodies for protein analysis, such as immunolocalization of the proteins on cellular and subcellular level.
However as this approach relies on expression of Cre by a specific promoter, it is irreversible.
Currently, identification of resting human Treg cells relies on expression of high levels of CD25 and expression of FOXP3.
In addition, any approach that relies on expression profiling cannot distinguish between directly and indirectly regulated target genes.
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