The bigger shift for The Times has been from a news organization that survived primarily on advertising — it generated $900 million in ad revenue last year, compared with $2 billion in 2002 — to one relying on circulation and consumer products.
Netflix and the internet have eaten into the DVD market, the independent sector is flailing, and the real opportunities are either in big-budget event movies for the happy few like him, or in low-budget comedies, or in radical new ventures on the internet that probably have no initial studio backing at all, and rely on viral circulation and word of mouth to get attention.
Cooling via the nasopharynx therefore offers the ability to cool across the thin cribriform plate via both direct conductive mechanisms that do not rely on spontaneous circulation as well as indirect haematogenous mechanisms.
We believe that the vascular anatomy of the nasal cavity allows transfer of venous blood from paranasal mucous membranes to the dura mater and may transmit temperature changes via both direct conductive mechanisms that do not rely on spontaneous circulation as well as indirect haematogenous mechanisms via dural vessels.
Species with poorly developed or no septa generally have no blood vessels and rely on the circulation within the coelom for delivering nutrients and oxygen.
Recently it has been demonstrated that prostate tumor growth may rely on systemic circulation levels of steroids and on local steroid production by prostate cancer cells [ 8, 13, 14].
In the standard business model, newspapers rely on revenues from circulation and advertising to pay for news coverage and generate healthy profits.
In contrast to the failure of static measures, a novel set of predictors that rely on perturbing the circulation accurately foretell whether fluids will augment cardiac output.
To cool its reactors, for example, Indian Point relies on the circulation of more than a billion gallons of water a day from the Hudson.
For instance, the material unity of natural philosophy in the 16th and 17th centuries relied on the circulation, transformation and application of objects, in their concrete and abstract representations (Bertoloni-Meli 2006).
