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Chelation of Ca2+ with 5 mM EGTA did not prevent immunoprecipitation of COX-2 by hrNuc (Fig. 5B), indicating that the association between the two proteins does not chiefly rely on availability of Ca2+.
Moreover, these evolutionary covariation methods [ 77, 78] rely on availability of hundreds of homologous sequences.
Instruments such as the CCI rely on availability and accuracy of medical records and as such, may be limited in its utility for clinical and research purposes.
However, development of EBCPGs led by methodologists would rely on availability of methodologists and funding, and this is unlikely to be achieved in hospitals.
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Limited proteolysis proved critical for most of the current exocyst structures; however, this strategy relies on availability of at least slightly soluble protein.
Reducing the burden of disease relies on availability of evidence-based clinical practice guidelines (CPGs).
This retrospective review relied on availability and completeness of investigation documents.
Pre-clinical development of anti-cancer therapeutics relies on availability of relevant and reproducible in vivo tumour models.
A possible reason the knowledge base on undocumented migrant health status was poor is because this often relies on availability of routine data.
33 The tiered approach (although deemed cost-effective) is a complicated process that may be difficult to enforce and relies on availability, experience, and judgment of pharmacists.
The current clinical management of breast cancer relies on availability of robust clinicopathological and individual molecular prognostic and predictive factors to support decision making.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com