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What selective advantage does this relocation of genes confer?
The WGD possibly increased transposition and chromosomal breakages leading to the relocation of genes.
Relocation of genes outside the cluster would likely occur by transposition for two reasons.
This apparent relocation of genes raises a number of interesting questions.
Additionally, the mechanism of relocation may also reveal insights into the factors driving the relocation of genes from the neo-X to the autosomes.
These studies, though, did not always observe a relocation of genes toward or away from chromocenters/nuclear periphery according to their expression status (reviewed in [ 28]).
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This finding suggests that the analyzed gene pairs diverged relatively recently, permitting a test of the hypothesis that the observed rearrangements occurred according to the "permutation-by-duplication" model [ 20] or to the alternative model, involving intragenic relocation of gene segments.
In this study, B lymphocytes were investigated, and a relocation of active genes away from chromocenters was observed, whereas silenced genes were found to colocalize with chromocenters (Brown et al. 1997).
Moreover, silencing of duplicate genes can have an indirect effect on adaptive evolution by causing genomic relocation of functional genes.
This megaplasmid probably acquired genes from diverse bacterial species before its capture by the ancestral Vibrio; subsequent relocation of essential genes from the chromosome to the megaplasmid completed its stable structure.
Thus, relocation of these genes cannot be linked with the recent TE activity.
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