Sentence examples for relieved restriction from inspiring English sources

Indeed, we found that A51R expression relieved restriction to VSV replication in each of the three additional Lepidopteran cell lines tested, including an L. dispar embryonic cell line (LdEP), a Spodoptera frugiperda-derived cell line (Sf9), and a Manduca sexta-derived cell line (GV-1).

These investigators found that tetherin can convey resistance to particle release when expressed in permissive cells, and that depletion of tetherin from restrictive human cells relieved the restriction.

In marked contrast to the results with CAML knockdown, depletion of tetherin relieved the restriction of particle release.

Stable depletion of tetherin relieved the restriction to particle release in HeLa cells, while stable depletion of CAML had no effect.

We reasoned that these cells have substantial levels of CAML (Fig. 1B), and that if CAML exhibited independent restriction of particle release that tetherin depletion alone should not relieve the restriction.

Thus, CsA accentuated the restriction of Ref1 (Trim5α or other host factors [45]) in human cells, while greatly relieving the restriction of LV-1 in other species.

In particular, depletion of CAML did not relieve the restriction to particle release in HeLa cells.

Remarkably, depletion of CAML also failed to relieve the restriction of Vpu-deleted virus (NLUdel, supernatant lane 8).

These results thus failed to support those in our previous report indicating that CAML depletion in HeLa cells relieves the restriction to particle release.

These results are consistent with previous reports indicating that tetherin knockdown alone is sufficient to relieve the restriction to particle release.

Together these results indicate that A51R is an early VACV protein necessary to relieve the restriction of VSV in LD652 cells.