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Deletion of site A in a transiently transfected MYC reporter gene construct has been reported to relieve suppression of MYC promoter activity [6].
Upregulation of NP mRNA, protein levels, polymerase activity as well as viral titers in API5-depleted cells are clear indicators that viral replication is inhibited by the host factor API5. NP interacts and downregulates API5 to relieve suppression of the E2F1 APAF1 apoptotic pathway.
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Upon ethylene binding, the receptors inactivate CTR1, thereby relieving suppression on the downstream signaling elements.
Cleaning one body part reduces the sensory drive to its motor program, which relieves suppression of the next movement, allowing the grooming sequence to progress down the hierarchy.
Cleaning one body part reduces the sensory drive to its cleaning movement, which relieves suppression of the next movement, allowing the grooming sequence to progress down the hierarchy.
Inhibition of NF- κB could suppress the antiosteoblastogenic activity of TNFa and relieve the suppression of BMP2-induced Runx2 expression mediated by TNFa.
It has been reported that PLK1 inhibits p53 transcriptional activity via direct binding; thus, inhibition of PLK1 by NF-YA should relieve its suppression on the p53 activity.
This suggests a natural selection for sequences which suppress IL-12 secretion by DC and against mutations which relieve such suppression.
This means that transcription of a gene will relieve translational suppression on its own mRNA and others that are regulated by the same miRNA.
This would relieve the suppression on NANOG.
mTOR directly phosphorylates the 4E-BPs (eIF4E-binding proteins), which are inhibitors of eIF4E, to relieve translational suppression, whereas Mnk phosphorylates eIF4E to stimulate translation.
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