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Notwithstanding this limitation, our results provide information that is helpful for the future development of a reliable PET ligand for human AMPA receptors.
Our results are of high interest with regard to multicenter comparisons and anticipated multicenter studies, which require a high degree of standardization in order to provide reproducible and reliable PET data in all sites performing amino acid imaging of brain tumors.
Human imaging studies, using SPECT imaging agent 5-123I-iodo-A-85380 and PET imaging agent 2-18F-fluoro-A-85380, have also identified an increase in receptor density among smokers versus nonsmokers, suggesting 2-18F-fluoro-A-85380 to be a reliable PET method for further tobacco studies [12, 13].
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Kim Vogt, Spotwag's co-founder, said she started the service with her co-founder Chris Wake after they both repeatedly struggled to find reliable pet-sitters for their dogs.
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Advantages of the trimodality PET/CT-MRI system include a more accurate attenuation correction, reliable PET-quantification, softrior softissueue contrast and a higher imaging flexibility that improves diagnostic accuracy for PCa.
The authors concluded that F-BAY-4367 F-BAY-4367 F-BAY-4367ET isaginotof reliablet disease, but is able to visualize primary tumours in a subset oforatients [ 130].
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