Suggestions(1)
Exact(2)
Our goal is to prove the principle that a single DNA vaccine can provide reliable immunity against PC in the MatLyLu (MLL) translational tumor model.
Some vaccines induce reliable immunity that lasts for many years, while for some diseases there is no effective vaccine at all.
Similar(58)
They have a favorable safety profile and induce reliable protective immunity against viral strains which are similar to those present in the vaccine.
As there is no reliable passive immunity against pertussis in newborns, indirect protection by reducing the risk of transmission from close contact persons has been put forward as the so called "cocoon strategy" [ 9- 11].
This method was simple and highly sensitive and allowed for the rapid and reliable determination of immunity to VZV (Sauerbrei et al. 2004).
All these results suggest that immunization with tobacco leaves expressing SAG1 is a reliable system to generate immunity, which could be boosted by heterologous prime-boost inoculation regimens.
Multiple studies have examined the use of oral fluids in modified serum-based assays aiming to replace serum in antibody detection for hepatitis A. However, the reliable detection of HAV immunity in oral fluid requires an extremely sensitive assay; most immunoassays designed for serum antibody determination lack sufficient sensitivity for this purpose.
A major limitation towards the achievement of this goal is a lack of reliable biomarkers of protective immunity against M. tuberculosis (Mtb).
Furthermore, as mentioned earlier, multifunctional CD4 T cells appear to be more reliable indicators of protective immunity than assays that screen for IFN-γ alone [26] [28].
Based on our experience in mice, we infer that when a live HSV-2 virus is used as the immunogen, then serum levels of gD2-antibody provide a reliable index of protective immunity against HSV-2.
Despite the lack of reliable biomarkers of protective immunity against M. tuberculosis (Mtb), it is currently considered that these vaccines should elicit anti-mycobacterial CD4+ effector T cells producing type 1 cytokines, as highlighted by the severity of mycobacterial infections when interleukin (IL -12/interferon (IL -12/interferonr tumor necrosIFN -γtor (TNF)-α [7] responses are IFN -γed.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com