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In the absence of withdrawal reporting, information on handling of possible dropout data and the impact of dropouts on the reliability of trials is rendered suspect.
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Expert biostatistical support is needed to ensure the validity and reliability of trial results.
Sponsors should focus on trial activities essential to ensuring human subject protection and the reliability of trial results.
The reliability of trial reports cannot be assessed without having access to the full protocols.
267 The validity and reliability of trial data depend on the quality of the data collection methods.
Many in the public health community question the reliability of these trials.
This approach not only will improve the reliability of preclinical trials performed on these large animals but will also hopefully speed up the discovery of new potential treatments for DMD.
The agency is supposed to evaluate whether any conflicts that are uncovered undermine the reliability of the trial data, and if so, how tainted data should be handled.
To guarantee the reliability of the trial, the calculation yielding the larger sample size was used.
Peer reviewers and other readers may benefit from this knowledge because it is notoriously difficult for them to evaluate the reliability of a trial's findings.
But while China's State Food & Drug Administration approved the drug, named Gendicine, the U.S. FDA hasn't yet, mainly because of concerns over the reliability of its clinical trials.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com