Exact(57)
The base PEV reliability overestimates the reliability of selection in selected populations because it is computed from PEV and the base additive genetic variance.
These results not only show which processes contribute to the reduction of the reliability of selection in selected populations but also that the base PEV reliabilities overestimate the reliability of selection in such populations by using the base additive genetic variance instead of actual additive genetic variance of selection candidates.
A recent study [ 16] showed that base PEV reliability may substantially overestimate the reliability of selection for selected populations, and that the equilibrium value of the latter, i.e., the equilibrium reliability, can be predicted from the parameters of unselected populations.
The base PEV reliability and the reliability of selection are equivalent for unselected populations (See Appendix) but not for selected populations, because selection reduces additive genetic variance and therefore also the reliability of selection [ 9, 11– 15].
The simulations showed that, for selected populations, the base PEV reliability substantially overestimates the reliability of selection of EBV that are mainly based on old information from the parental generation, as is the case with pedigree-based prediction.
Commonly, the base additive genetic variance (σ A,02) is used to compute the base PEV reliability (A6), while the reliability of selection is computed as squared correlation between the EBV and BV in a selected group of individuals (A1) that do not necessarily have the same additive genetic variance (σ A 2) as the base population.
Figure 10 Reliability of selection ( n = 5).
The resulting PEV reliabilities matched the reliability of selection within the bounds of sampling.
Similar(3)
The cloning capability and reliability of selection-free PCR recombination cloning with pOmni were validated through cloning of 6 DNA fragments with length from 315 to 4557 bp, and the dual-expression function of the vector was verified through the cloning and expression of EGFP in E. coli BL21 and HeLa cells.
The base PEV reliabilities of these EBV were compared to the corresponding reliabilities of selection.
In general, realized genetic selection intensities reflected the reliabilities of selection for both the random selection scenario and the BLUP selection scenario and confirmed that base PEV reliabilities overestimate reliabilities of selection in the BLUP selection scenario.
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