Of these, dAPs have been observed up to 25 ms later and can be distinguished from subsequent sAPs based on their high reliability of occurrence (>80%), low jitter (160 µs), and consistency of waveform across trials [24] [26] (Fig 2; see Methods for a description of automated dAP detection).
6) In Figure 4D, observed increase in cosine similarity could simply be result from increased reliability of occurrence of calcium transients, not from increased population pattern similarity.
To ensure reliability of phrases, occurrences and frequencies of common phrases within single IDIs and across IDIs were compiled and noted.
UMMI finds several highly reliable constraints at each time point (Additional file 1, Table S1) that pass a reliability threshold (frequency of occurrence in the learned models) of 0.1.
(B ) The reliability of calcium transients occurrence across three repetitive V2L stimulations was calculated by Cronbach's alpha.
DOI: http://dx.doi.org/10.7554/eLife.02726.008 10.7554/eLiFigure26.009 Figure 4 figure supplement 1. Percentage distributions of neurons by dF/F in each conditioning group and reliability of calcium transients occurrence following three repetitive secondary visual cortex lateral area (V2L) stimulations.
In all groups, Cronbach's alpha of 'Before' and '2h' are not significantly different, suggesting that the increase in cosine similarity may be caused by a change at the network level; not by an increased reliability of calcium transient occurrence.
In addition, the increased cosine similarity was not due to increased reliability of Ca2+ transients occurrence in response to three repetitive V2L stimulations, because the reliability calculated by Cronbach's alpha did not change between 'before' and '2 hr after' in any of the conditioning groups, including T1.
These results indicate that only T1 conditioning improved the pattern similarity in PFC neurons, and the increase in pattern similarity could be the result of circuit (network) modification, and not simply the result of increased reliability of Ca2+ transients occurrence or an increased number of high responding dF/F neurons.
Every system is supposed to be analyzed for possible failure processes and failure criteria, probability of occurrence, reliability of basic components used, redundancy, possibilities of human errors in the production, and other uncertainties.
For more accurate analysis of crash characteristics, data in smaller time window, e.g., 1 min even 30 s, are highly recommended to improve the reliability of statistics, since crash occurrence is significantly associated with the short-term turbulence of traffic flow [1].
