Sentence examples for reliability of calls from inspiring English sources

The need for additional replication may also have been reduced by using elevated amounts of genomic DNA and the use of end-labeling rather than BioPrime may have increased the reliability of calls.

Initial laboratory quality assurance relied on the GenCall score, a quality metric indicating the reliability of called genotypes that is generated by the BeadStudio software.

The quality value percentage is a quality metric that indicates the reliability of called genotypes generated by the SDS software.

In this case, a PNPG value of 0.05 was still considered as the threshold to determine the reliability of call for a SNP locus.

The same gold standard dataset was used by Major et al. (2013), who also examined the reliability of calling HLA alleles using NGS, but using the 1000 Genomes alignment data, and showed that this publicly available dataset can be used for this purpose, after appropriate filters (e.g., coverage) are applied.

The barrier called lack of clarity, relevance and reliability of research calls for change in researchers' objectives and methods, but we need to know what policymakers define as clear, relevant and reliable research, and why and when policymakers will use such research.

Furthermore, since each laboratory or company may have its own mutation calling algorithm, this lack of clarity means there is no consensus on how to ensure the reliability of mutation calls.

The reliability of genotyping calls drops when the minor allele frequency (MAF) falls below 5%.

Depth of coverage variation and strand bias were identified but generally did not impact reliability of variant calls.

NGS has several important advantages over DNA microarrays that can improve the resolution, accuracy and reliability of variant calls [ 24].

All the aforementioned applications of the 1000 Genomes Project SNP data in HLA genes are dependent on the reliability of genotype calls at each SNP.