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The team added that "open access to all relevant trial data is a necessity to make ethical decisions in healthcare".
This means attempting to identify every relevant trial of a given question (including studies that have never been published), choosing the best ones using clearly defined criteria for quality, and combining the results in a statistically valid way.
Lee and colleagues (2013) argue that journal editors must take much more action than is currently taken to require that researchers make their raw data and other relevant trial information available to enable peer reviewers to conduct their work adequately.
For each GLM, we coded four relevant trial types based on the outcome at retrieval.
Nineteen reviews (59%) did not explore potential causes of heterogeneity for relevant trial groups.
We employed a functional measure as the primary outcome, because timed function testing is a clinically relevant trial endpoint in DMD [32].
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Like most medical journals, The American Journal of Psychiatry does not require company sponsors of drug trials to divulge information about all relevant trials of a medication.
The results, be they positive or negative, could then be put into context with other relevant trials of the same drug.
The reference lists of potentially relevant trials, meta-analyses and systematic reviews were also searched.
Most of the relevant trials recruited hospitalized patients from different populations, especially the noncritically ill patient groups (Table 2).
To avoid omitting relevant trials, conference abstracts and reference lists of all identified related publications were also searched.
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