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Most relevant to the screen presented here are observations that Htz1p recruitment to centromeres is dependent on both the NuA4 and SWR complexes and that deletion of HTZ1, and genes for components of both the SWR and NuA4 complexes, result in chromosome segregation defects comparable to those we report here for actin mutants (Krogan et al. 2004).
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The methods described are particularly relevant to the screening of compounds for cancer chemopreventive activity.
The resulting images are uploaded into the Sesame laboratory information management system database where they are associated with other data relevant to the crystallization screen.
The assay design principles in this paper are also relevant to the HRM screening of other germline mutations.
The ERAP1 models we generated exhibit structural characteristics that appear highly relevant to the peptide library screen results.
An existing systematic review on FASD screening and diagnosis [ 35] was used to identify literature relevant to the design of screening for FASD in Australia.
Data relevant to this screening program, including the demographics of screened subjects, the results of FIT, endoscopic findings, and the results of histopathology, were all stored in a central database.
In Factor C, shown in Table 6, there are only interpersonal and informational roles indicating a managerial style of collecting external information relevant to the company, information screening and dissemination to employees, and instruction and verification that the information disseminated has been understood by the interested parties.
If the false-recent rate is accurate and relevant to the population being screened, the correction works quite well, as shown in the analysis of the VAX003 data (Table 2).
Data items included the population description, study details and the main findings relevant to the population-based screening criteria 40.
The result most relevant to the design of screening programs, however, is the incidence of preproliferative retinopathy, which in the U.K. is the diagnostic threshold for referral to specialist eye care.
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