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Using three different proteins - human ubiquitin, T4 lysozyme and enzyme cyclophilin A - we show that QAA identifies and characterizes the conformational sub-states relevant to function.
Functional analysis of the human airway basal cell signature using a diverse set of analytic tools identified a number of gene categories relevant to function of the cells to maintain the structural integrity of the airway epithelium.
Domains considered relevant to function were usual activities and self care.
Due to posttranscriptional regulation, transcript levels only partially predict protein abundance, the latter being more directly relevant to function.
The circulating levels of bisphosphonates are extremely low as they are rapidly absorbed by bone, suggesting that circulating levels are not relevant to function.
One potential advantage of IHC is that the system is designed to measure protein, rather than RNA, which is more relevant to function.
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These CCR4-specific amino acids are most probably relevant to functions common to and specific for all yCCR4-related proteins (see Discussion).
The objective of this stage was to gather the opinions from international experts on which ability and disability concepts were considered relevant to functioning in ADHD.
Here, we introduce 'MitoInteractome', a consolidated multi-species database for mitochondrial research that integrates information relevant to functions, pathways, diseases, non-synonymous SNP effects, protein-protein interactions, and physico-chemical properties.
In this work, we demonstrate that the spatial conformation of the human genome is relevant to gene function similarity and is useful for gene function prediction.
Hence, previous studies of Prdm3 function in haemopoiesis and leukaemogenesis may be relevant to Prdm16 function in progenitor cells in the CNS.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com