Exact(23)
In total, the systematic literature searches resulted in seven clinically relevant therapy studies.
A better characterization of this population may assist and direct prevention campaigns and relevant therapy of MOH.
In the direct measurement the most relevant therapy characteristics were "drug does not affect or not affect appearance much", "self-application of the drug is possible" and "rarely occurring longer periods of nausea and diarrhea".
We aimed to build a multivariable model including the best general ICU score, the best biological variable of hepatic failure, and the most relevant therapy performed at ICU admission.
The most relevant therapy characteristics represented by mean assessments of more than 90 points were: – Self-application of the drug is possible, – Drug has very high efficacy, – Long term (hidden) side effects are unlikely.
In the direct measurement the most relevant therapy characteristics were "Self-application of the drug (at home or on-the-go) possible", "Drug has very high efficacy (reduction of viral load)" and "Long term (hidden) side-effects (e.g. organ damage) is unlikely".
Similar(37)
ALS is a particularly challenging disease for designing relevant therapies, and presently no effective treatment exists.
Advances within the field of bone tissue engineering will likely overcome these challenges and lead to more clinically relevant therapies.
However, numerous challenges must still be overcome in order to translate these techniques into clinically relevant therapies.
Clinicians require radiologists who understand the clinical questions, keep updated with the most recent advances in the disease processes and have knowledge of the relevant therapies.
The need for a disease-specific instrument to capture patients' symptomatic toxicities according to the relevant therapies has been emphasized [29].
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