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Relevant stiffness and compliance contribution tensors are derived for spheroidal inhomogeneities.
Finally, the procedure is applied to experimental data to obtain relevant stiffness, viscous and viscoelastic parameters associated with the system.
Here, we have developed a polydimethylsiloxane (PDMS -based substrate caPDMS -basedmulating the physubstratelly relevant stiffness of both venous (7 kPa) and arterial (128 kPa) tissues.
Remarkably, fibrous structure and physiologically relevant stiffness of hydrogels cooperatively enhanced smooth muscle contractility and pharmacological responses to vasoactive drugs at both the single cell and intact tissue levels.
Data gathered during one annum of monitoring was used in conjunction with a finite element model and a meta model, resulting in an estimation of the relevant stiffness parameters for both the cold and the warm condition.
While some somatic cells may durotax in physiological gradients [20], each mature cell type exhibits lineage specific behavior within a physiologically relevant stiffness range [4], [6], [25].
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The PCL sheath exhibited comparable mechanical properties to commercially available nerve conduits, and the O-CCH filler showed a physiologically relevant substrate stiffness of 2.0 ± 0.4 kPa.
At each time step, the calculations performed in DEM alternate between integrating equations of motion for each particle, and applying the force displacement law at each contact, through which the contact forces are updated based on the relative motions between two particles and their relevant contact stiffness.
Matrigel is a thermally setting, ECM composite material that assumes tunable, tissue-relevant mechanical stiffnesses that are protein concentration dependent.
This demonstrates that there is a clinically relevant reduction in stiffness at all time points during the study.
The pathological condition produced relevant effect on stiffness, which significantly increased in RA patients relative to normal subjects (about +42% over the half-cycles; F 1,5) = 23.66, p < 0.0001).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com