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Instead we show a new Figure 4 which represents the dynamics of fsta and bambi expression along with indicators for BMP activity (anti-pSmad 1/5/8 immunohistochemical stainings and BRE::GFP expression) at relevant stages for optic cup formation.
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This literature search forms the rationale for the relevant stages of the assessment guideline.
The goal of this study was to estimate true and false positive rates of the two-marker blood test for screen-relevant stages of colorectal neoplasia, namely advanced adenoma and CRC of specific stage, and across the full spectrum of non-neoplastic pathologies encountered in the colon/rectum when screening a large population.
For clinical diagnosis the two most relevant stages are MCI and dementia.
An in situ screen for Cx genes expressed at the relevant stages and in relevant tissues identified Cx26 and Cx32.
To determine the relevant stage, five characteristics for each sex have to be assessed (growth spurt, skin changes and body hair for boys and girls, breast development and menarche in girls, voice change and facial hair growth in boys).
After adjustment for age-group, year of diagnosis and (where relevant) stage, the only diagnostic group for which there was a significant sex differential in relative survival was leukaemias, where girls were significantly less likely (HR=0.76; (0.62–0.93), P=0.007) than boys to die within 5 years of diagnosis (Table 3).
The main analysis used all relevant stage data from NCRS (see Additional file 1: appendix 1 for description of collection of stage data).
Such nodes contain relevant staging information.
Aged females are the most relevant mosquito life stage for malaria transmission as it takes approximately two weeks for Plasmodium parasites to mature within the mosquito to an infective stage [ 24].
As chironomids spend most of their lifetime as larvae and usually even do not feed as imagines during their few days in this stage [ 31], the larval stage is in general regarded as the relevant life cycle stage for ecological studies [ 32].
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com