Sentence examples for relevant pathways in which from inspiring English sources

Gene selection in candidate studies relies on 1) known functions of gene sets sharing biological processes, and/or functionally interacting within biological networks; or 2) the mode of action of the environmental factors through relevant pathways in which genes are involved [ 1].

The preclinical evidence is thus consistent with a physiologically relevant pathway in which thrombin thrombomodulin dependent APC generation triggers protective anti-inflammatory effects in vivo.

In this way, it may be possible to discern a physiological role for the Maestro gene and identify the relevant molecular pathways in which it acts.

Metabolic disorders like obesity or diabetes are associated with high levels of cytokines which activate AD relevant pathways in neurons.

Instead, it can be used iteratively to calculate pathways of increasing length, which results in a dramatic improvement in performance for finding relevant pathways in large networks.

These results demonstrate that fly models can be employed for the identification of clinically relevant pathways in human cancer.

"By identifying the genes that are involved in determining outcomes in Crohn's disease, we can now focus on developing drugs that actually target relevant pathways ― which should provide more effective therapies," Lee explained.

When applied to the CD data set collected by the WTCCC, the method highlighted many relevant pathways which play a key role in CD as well as in other inflammatory diseases.

We focused on the two well-described, convergent pathways in which mTOR acts as key regulator: the PI3K-AKT-mTOR pathway and the RAS-MAPK-mTOR pathway.

Rheumatoid arthritis (RA) is a multifactorial, polygenic disease, in which the relevant pathways involved in its various stages are poorly understood.

The way this is achieved is largely dependent upon the signal transduction pathway in which the interaction is thought to be functionally relevant.