Sentence examples for relevant off from inspiring English sources

These investors will not have sweat it out in a Startup Alley, but rather, if selected, expected to help lead the conversation at a relevant Off The Record session.

Design, synthesis and structure activity relationships study of the HTS-derived hit led to the identification of 5-chloro-2- 3,5-dimethylphenyl -4- 4-methoxyphenoxy pyridazin-3(2H)-one lead molecule with submicromolar antagonist activity at the target receptor and high selectivity against a panel of therapeutically relevant off-target proteins.

Further these results show that RNAi screening enriches for siRNAs with relevant off-target effects.

In E1A- HRAS G12V -transformed Craf −/− MEFs, dabrafenib fails to confer a significant growth advantage, suggesting that in the absence of significant paradoxical ERK activation, dabrafenib does not have a relevant off-target effect that results in a growth advantage.

With pharmaceutical compounds as baits, drug targets and toxicity-relevant off-targets can be discovered in an unbiased proteomic screen.

From 4067 records relevant to off-label drug use in our full gold standard set, 3846 records were retrievable from EMBASE.

We considered documents as relevant to off-label drug use, if they referred to any human drug outside the approval purposes, in terms of different dose, indication, route of application or for another age group.

Overall, the most impressive rooms are the subtle ones, where the challenge of marrying the fanciful and relevant comes off effortlessly.

We found that the age of 45 was a relevant cut off point.

We chose a low cut-off indicating mood disorders and not a clinical relevant cut-off screening for major depression.

First, IPD meta-analysis can address bias from the selective reporting in publications of only well-performing cut-off thresholds since accuracy can be evaluated across all relevant cut-off scores.