These observations in mice led us to investigate the immunogenicity of a naked DNA encoding the HIV-1 LAMP/gag antigen formulation in Rhesus macaques, a relevant animal model for testing HIV vaccines for potential use in humans.
Our work with the adult OVX rabbit shows that it is a relevant in vivo bone model for testing selective inhibitors of the human CatK enzyme [ 13].
With the increasing number of contaminants in the marine environment, various experimental organisms have been "taken into labs" by investigators to find the most suitable environmentally relevant models for toxicity testing.
The reality in which our study was conducted would, under those circumstances, be much more relevant and could serve as a model for testing ways of dealing with this problem in many countries in the western world.
Taken together with the demonstrated capability of NTG to induce spontaneous-like migraine attacks in migraineurs, these findings suggest that NTG-potentiated formalin test is a relevant model for investigating migraine circuitry.
We have never taken the straight ideal of a monogamous life-long relationship as being a relevant model for us.
We used model selection techniques and linear models for testing relevant factors affecting specialist species in grassland fragments.
Among the most interesting cell types that can be derived from hESC are DA neurons, both because of their potential use as a therapy for Parkinson's disease (PD), and as in vitro models for testing drugs relevant to neurodegenerative disorders, drug abuse, and addiction.
In contrast, primary cultures retain many of phenotypic characteristics of the original tissue, including normal physiological functions, and, therefore, can be highly relevant models for gene discovery, target validation, drug testing, and development of biomarkers.
