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These data indicate that home cage wheel running is a sensitive, reliable, and clinically relevant method to assess migraine pain in the rat.
The present data indicate that depression of home cage wheel running is a reliable and clinically relevant method to assess migraine pain in laboratory rats.
The primary goal of the present study was to test the hypothesis that home cage wheel running is a sensitive, reliable, and clinically relevant method to assess the duration and magnitude of migraine pain in laboratory rats.
The goal of the present study was to test the hypothesis thatdepression of home cage wheel running is a reliable and clinically relevant method to assess migraine painin rats.
The use of home cage wheel running should help unveil the pathophysiology underlying migraineheadache and provide a clinically relevant method to assess the anti-migraine efficacy of novel therapeutics.
Depression of wheel running is also a clinically relevant method to assess migraine pain in rats in that it mimics the reduction in normal physical activity characteristic of migraine in humans [12].
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Taken together, these data prove the ability of hESC-DA neurons to provide extensive reinnervation of the host striatum and begin to restore DAergic neurotransmission 5 months posttransplantation, using clinically relevant methods to assess graft function, in the absence of significant adverse events.
FAC will remain relevant, because it is a cheap and easy-to-implement method to assess protein ligand binding.
However, demonstrations of functionality in living systems necessitates a method to assess the in vivo stability of the relevant nanostructures.
The bias formula was used as the basis for proposing a new method to assess the sensitivity of estimates of treatment effects to omission of relevant covariates.
The World Series champion Chicago White Sox use a different popular method to assess their expected victories.
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