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For this analysis, two of these six elements were relevant, "initiates interaction with others" and "pursues involvement in the life of the facility".
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Also, fusions of TMPRSS2 (transmembrane protease, serine 2) with different members of the ETS transcription factors family are likely relevant initiating factors in this neoplasia [ 8].
Thus, although initial β-catenin signaling seems to be relevant to initiate wound repair, crosstalk of Wnt/β-catenin with other pathways might interfere with proper repair and result in fibrosis (Königshoff and Eickelberg, 2010; Ulsamer et al., 2012; Tanjore et al., 2013; Lam et al., 2014).
Buyers are far more responsive to social media messages around relevant topics initiated by the sales person or the buyer.
The observation that lupus autoantigens are selectively clustered in apoptotic surface blebs initially focused attention on apoptosis as an important pathway, upstream of inflammatory processes, which may be relevant in initiating and propagating SLE [2], [3].
Moreover, it is important to distinguish viable from apoptotic CTCs to detect and profile the most relevant metastasis-initiating CTCs.
Information on current survival rates may be relevant before initiating therapies for women or men with a BRCA1 or BRCA2 mutation.
The significance of this is not entirely clear given that the secreted protein represents the biologically relevant fraction initiating HIF-mediated angiogenesis.
The approach may be relevant to initiating and sustaining a change in relation to a range of complex and chronic diseases which involve a wide range of service delivery providers in primary health care.
Experts' opinion regarding disease parameters relevant to initiate TNF-α-blockers in RA patients only slightly differed from those applied in clinical trials, but the parameters' threshold values were considerably lower.
The failure to identify a relevant molecular initiating event for methoxychlor in HTS assays demonstrates the current limitations of in vitro screening in predicting in vivo activities of chemicals that are metabolically activated.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com