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The report notes it is likely that up to 50% of children have latent tuberculosis, with "their risk of developing active tuberculosis increased by young age, recent migration and social stressors, all of which are relevant in this setting".
At least two scenarios may be relevant in this setting.
Given that study attrition is less relevant in this setting, we excluded this item.
The emerging concept of fungal prophylaxis in patients with recurrent abdominal perforation could be relevant in this setting [ 38, 39].
The available literature on anaemia and pregnancy outcome is mainly devoted to severe iron deficiency and sickle cell disease and is not relevant in this setting.
The high prevalence of PIK3CA mutation in metastatic or recurrent breast cancer suggests that PI3K-pathway-targeted therapeutics will be clinically relevant in this setting.
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As found in relevant studies in this setting, 9, 25, 26 our results show that poverty indicators, such as household crowding, poor sanitation, and food insecurity, are prevalent.
In this study cause of death was stratified on cardiovascular outcomes but the findings of Nyström et al. are nevertheless relevant even in this setting as they suggest that we are not likely to underestimate CVD deaths in this study as a consequence of breast cancer deaths being reported more frequently among the patients than they would in a disease free population.
This was particularly relevant in the setting of an upcoming review by the Liaison Committee on Medical Education.
Therefore, the theoretical model could be regarded as consistent and clinically relevant in this specific setting.
All four items content in domain occupation were identified to be not relevant in this study setting because generally Malaysian mothers did not start working within a month or 40 days postpartum as they were still in the confinement period.
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