Sentence examples for relevant hallmarks from inspiring English sources

I would like to outline only some of the most relevant hallmarks of this change.

They were not recognized as mitochondrial pre-sequences by prediction software TargetP and Mitoprot, but possessed relevant hallmarks of targeting signals rich in small, hydroxylated, hydrophobic and positively charged amino acids (Table 1, Figure 1).

It has been also reported that WNT4 interferes with Ras-induced actin cytoskeleton reorganization; it is known that aberrant motility and invasive ability are relevant hallmarks of malignant tumor cells [ 27].

In contrast, we noted a consistent organization in all cell types with regard to two co-aligned networks, an active (ANC) and an inactive (INC) nuclear compartment delineated by functionally relevant hallmarks.

ANC and INC differ with regard to functionally relevant hallmarks, including a highly significant enrichment of RNA polymerase II and histone signatures for transcriptionally competent chromatin in the ANC, whereas the INC is enriched in marks for repressed chromatin.

One of the most relevant hallmarks of the ageing process is the accumulation of reactive oxygen species (ROS) due to the impairment of cellular mechanisms that protect against oxidative stress (reviewed in Finkel & Holbrook, 2000).

A clinically relevant hallmark of gliomas is their very infiltrative growth pattern.

Here, we portray potentially clinically-relevant hallmarks of cancer stem cells and focus on their recently appreciated properties of cell variability and plasticity, both of which make them elusive targets for cancer therapies.

In order to assess the effect of the different approaches in preventing/halting disease progression, we performed comprehensive time-course analyses examining relevant pathological hallmarks.

Again, several networks relevant to aging hallmarks were readily grouped together.

Given the diversity of the targets involved in the 11 hallmark areas, it was anticipated that inhibiting or stimulating a target relevant to one hallmark may have an impact on other targets that are relevant, especially if both are linked via signaling pathways.