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Thus, uncharacterized protein segments are likely to be a large source of functional novelty relevant for discovering new biology.
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Understanding the molecular changes within the tumor microenvironment during tumor progression may therefore be relevant not only for discovering potential therapeutic targets, but also for identifying putative molecular signatures that may improve tumor classification and predict clinical outcome.
In fact, whereas structured populations are statistically powerful for discovering relevant genomic intervals, they generally lack the statistical power needed for the isolation and the detailed characterization of individual QTL [ 19].
The evaluation shows that use of PathText 2 substantially improves on PubMed search for discovering relevant documents, that the annotations can support the development of heuristics for document ranking and that the task of determining document-reaction relevance is feasible using machine learning methods.
The potential for discovering additional contextually relevant molecular players in the pathway is enhanced by robust read-outs such as transcriptional reporter assays coupled with genome-wide RNAi libraries [9].
In summary, we have demonstrated that a mouse model of human GC provided helpful materials for discovering circulating miRNAs relevant to the clinical stage of DGC.
More than even YouTube, Showyou is the best app for discovering new videos that are contextually relevant.
Analyzing metatranscriptomes from microbial communities enriched under conditions relevant to industrial deconstruction of lignocellulosic feedstocks for biofuel production is a powerful technique for discovering potentially robust lignocellulolytic enzymes.
We considered that identifying consistent trends in protein accumulation above an arbitrary cutoff such as 1.5-fold was most relevant for the purposes of discovering protein candidates for hypothesis formulation related to ripening control.
We have used a range of proteomic analyses of serum and tissue from gastric cancer patients and relevant controls to discover biomarkers for gastric cancer.
Some practically relevant phenomena are discovered.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com