Exact(2)
Therefore, the high levels of HtrA1, which we measured in Gfap Cre Dicer f/f forebrains, might affect BMP signalling causing a relevant disruption of proper forebrain development.
The influence of this exposure cannot be determined; however, in a study by Liu et al., short exposure to low levels of light did not seem to cause relevant disruption of the pattern of IOP fluctuation [ 37].
Similar(57)
Detection and estimation of these developmentally relevant disruptions in small-world architecture at critical brain regions sub-serving cognitive, affective, and sensorimotor processes are vital for understanding the familial risk for early onset alcoholism as well as for understanding the pathophysiological mechanism of externalizing behaviors.
In addition, the JET auxiliary heating power will be upgraded to ∼45 MW, allowing access to ITER-relevant disruption and edge localised modes energy loss densities.
It was never entirely clear how relevant the disruption idea was outside of digital hardware.
Based on these past models of teratogenicity, the higher exposures represented by daily maxima could be more relevant to disruption of cardiac development.
Since EGR2 is a regulator of many neurologically relevant genes, disruption of normal EGR2 expression has the potential to influence many downstream targets.
Evidence of relevant signaling disruption in the absence of adequate developmental toxicology data should influence the size of the uncertainty factors used in risk assessments.
In an attempt to solve this problem, my team — which consists of myself, postdoc Cristina Rea, graduate students Kevin Montes and Alex Tinguely, and a dozen scientists at other U.S. and international labs — has built up large databases of measured parameters which we believe are relevant to disruptions, from several years' worth of experiments on several different tokamaks around the world.
To minimize this disruption, relevant tools are required that allow to manage change reliably.
The largest data gaps exist in end points relevant to endocrine disruption and mammary gland developmental effects.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com