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No patient experienced clinically relevant deterioration in disease parameters measured.
At the heart of this framework is the choice of an appropriate combination of models for the relevant deterioration processes and the uncertainty associated with these models and their input variables.
In the paper, after a general presentation of the main properties and of the most relevant deterioration phenomena of the principal parts of the monumental area, the methodology that is being used for the structural diagnosis, for the implementation of guidelines for the future interventions and for the maintenance of the restored conditions are presented.
Clinically relevant deterioration (≥0.5) was observed in 9.8-12.3%.
The percentage of patients with a clinically relevant deterioration from baseline was analysed by χ-tests.
Systemic hemodynamics, as a measure of safety, showed no relevant deterioration throughout the procedure.
Similar(27)
We aimed to establish an endpoint capturing clinically relevant deteriorations (diary events) that, when combined with severe exacerbations, create a composite outcome (CompEx).
The critical thresholds are regarded as clinically relevant deteriorations.
Thus, we deemed that the reduced efficiency in selected cognitive domains did not correspond to a clinically relevant cognitive deterioration.
However, no MwoA patients achieved scores below the available cut-off values, thus suggesting that the reduced efficiency in selected cognitive domains did not correspond to a clinically relevant cognitive deterioration.
We can, thus, suggest that MwoA patients with migraine symptoms needing medical consultations show "sub-clinical" neuropsychological impairments mainly affecting executive functions, i.e. a reduced efficiency of cognitive processes in the lack of clinically relevant cognitive deterioration.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com