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Of note, the study was not conducted in clinically relevant cell types.
The feasymptoticof mitigating thomogenizations concentration in the comethode by tunisg the fibre gradoptedrofile is shown.
Working with biologically relevant cell models provides researchers with more meaningful answers to their research questions.
Further, the subcellular localization of the nanoparticles was assessed in different relevant cell lines.
Mesenchymal stem cells (MSC) represent a promising and clinically relevant cell source for tissue engineering applications.
All prepared samples were tested in relevant cell culture using osteoblast-like cells (MG-63) to demonstrate their biocompatibility.
Creation of more physiologically relevant cell models in tissue culture is a requisite for advancing medical research.
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Besides visualizing cells, we were able to quantify beforehand known cell concentrations implanted in cartilage defects in a clinically relevant cell-concentration range.
We expect that this capability will illuminate the early events during physiologically relevant cell-cell contact including phagocytosis or synapse formation.
However, scientists are now able to convert patient fibroblasts into iPSCs and differentiate them into disease-relevant cell types.
These cells have been differentiated into ALS-relevant cell subtypes including motor neurons and astrocytes, among others.
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