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Such models could also allow the testing of disease-modifying therapies in ALI to generate relevant, reliable and predictable human pharmacodynamic, pharmacokinetic and toxicology data through analysis at the organ, cell, genomic and molecular level, before early phase clinical studies.
We screened a commercially available library of 1280 compounds (Sigma LOPAC1280) that contains marketed drugs and relevant structures with predictable activities and proven scaffolds directed against a wide range of known drug targets including GPCRs and protein kinases.
"It had become so boring and predictable and not relevant to them".
Their world is far removed from the auto world and even though some have shown a strong visceral connection to the car and motor racing, what they bring to the occasion is never predictable, sometimes socially relevant and almost always visually thrilling.
Was smooth and predictable.
Depressing and predictable.
Consistent and predictable wages.
Instead, Serbia was slow and predictable.
The reply was instant, and predictable.
Their hormonal aberrations are dramatic and predictable.
"They're just as boring and predictable".
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