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The strong association between cortisol responses to laboratory stress and cortisol AUCday provides evidence that despite laboratory stress testing involving short-term stimuli of limited real-life relevance, variations in cortisol responses nevertheless predict output over the day.
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Preliminary findings using the Yeast 7.0 FBA model show lack of growth for only one enzyme, but augmentation of the Yeast 7.0 biomass function to better simulate knockout of certain genes suggested physiological relevance of variations in three additional proteins.
The purpose of the present article is to assess the relevance of variation in the PaO2/FiO2 ratio with the FiO2 level.
In accordance with previous studies [ 27] our phylogenetic analyses of the BMP4 gene revealed a highly conserved sequence of the BMP4 region which would suggest a potential functional relevance of variation at this locus.
Most welfare economists agree in principle that to be interpersonally comparable (viz. to be of policy relevance), compensating variation should be corrected for income inequality by applying 'distributional weights' [ 44].
See related research by Karbing et al., We read with interest the report by Karbing and coworkers [ 1] in which they assess the clinical relevance of variation in the arterial oxygen tension (PaO2)/fractional inspired oxygen (FiO2) ratio, a widely used oxygenation index, alongside changes in FiO2.
Joshi, M. S. et al. Functional relevance of genetic variations of endothelial nitric oxide synthase and vascular endothelial growth factor in diabetic coronary microvessel dysfunction.
Particular attention has been paid, so as to identify any relevance between the variations in the controller's design parameter and the system's output response and performance.
The relevance of these variations for toxicity investigations should be investigated more closely.
The clinical relevance of FGF23 variations induced by vitamin D is an intricate topic beyond the purposes of this review.
Furthermore, robust and high-throughput functional models to interpret the relevance of genetic variations are urgently needed.
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