"ABC International's processes for curation and publication of content from other parts of the ABC include ensuring relevance, contextualisation, translation, editing for brevity, and consideration of rights and technical constraints.
The use of animal models and their relevance for translation of research results to the clinical setting are also discussed in order to provide the reader with a critical view.
Each of them has the maximal relevance with translation rate and the minimal redundancy with other features.
Quality of tissue formed and long-term in vivo stability are important parameters to consider when contemplating clinical relevance and translation.
Overall, these results highlight the relevance of translation efficiency allowing the rapid changes in gene expression necessary for differentiation.
Collectively, these observations emphasize the relevance of translation regulation by a plethora of SyAS- foci in neuron development and homeostasis.
Of relevance to translation from pathobiology to clinical application, synovial CXCL13 mRNA has been recently shown to co-vary with the level of local inflammatory biomarker expression and has been thus proposed as a surrogate marker of synovitis [ 15].
And, the risk of ambiguous anticodon-to-aa assignment, while originally of crucial importance for primordial coding in the RNA world, was of less, if any, relevance for translation which most likely evolved later.
In addition, the differentially translated genes between E and MT show a wider dispersion of the nRPK values than the one observed for the transcriptome (compare Figure 2B and C to Figure 1B and C, see also Figure 3 and the Additional file 4), reinforcing the relevance of translation control on gene expression regulation.
Furthermore, we demonstrate the reliability of mathematical modelling as a tool to analyse and deduce key factors within an empirical data set and highlight its relevance to the translation of regenerative medicine strategies.
